Photo of Qiushi Chen

Qiushi Chen

Assistant Professor


  • Industrial and Manufacturing Engineering

302 Leonhard Building


Personal or Departmental Website

Research Areas:

Operations Research; Operations, Services, and Analytics

Interest Areas:

Stochastic dynamic modeling, simulation, system dynamics models, with applications in health analytics, cost-effectiveness analysis, medical decision making, health policy modeling




  • BS, Industrial Engineering, Tsinghua University, 2010
  • Ph D, Operations Research, Georgia Institute of Technology, 2016


Journal Articles

  • S Chen, Qiushi Chen, J Yang, Lin Lin, L Li, L Jiao, P Geldsetzer, C Wang, A Wilder-Smith and T Bärnighausen, 2020, "Positive impact of facility-based isolation of mild COVID-19 cases on effectively curbing the pandemic: a mathematical modelling study.", Journal of travel medicine
  • Qiushi Chen, T Ayer, M G Adee, X Wang, F Kanwal and J Chhatwal, 2020, "Assessment of Incidence of and Surveillance Burden for Hepatocellular Carcinoma Among Patients With Hepatitis C in the Era of Direct-Acting Antiviral Agents.", JAMA network open, 3, (11), pp. e2021173
  • S Chen, Qiushi Chen, W Yang, L Xue, Y Liu, J Yang, C Wang and T Bärnighausen, 2020, "Buying Time for an Effective Epidemic Response: The Impact of a Public Holiday for Outbreak Control on COVID-19 Epidemic Spread.", Engineering (Beijing, China), 6, (10), pp. 1108-1114
  • Y Zhuo, T Hayashi, Qiushi Chen, R Aggarwal, Y Hutin and J Chhatwal, 2020, "Estimating the price at which hepatitis C treatment with direct-acting antivirals would be cost-saving in Japan.", Scientific reports, 10, (1), pp. 4089
  • Jagpreet Chhatwal, Qiushi Chen, Xiaojie Wang, Turgay Ayer, Yueran Zhuo, Naveed Z. Janjua and Fasiha Kanwal, 2019, "Assessment of the feasibility and cost of hepatitis C elimination in Pakistan", JAMA Network Open, 2, (5)
  • Qiushi Chen, Turgay Ayer, Emily Bethea, Fasiha Kanwal, Xiaojie Wang, Mark Roberts, Yueran Zhuo, Stefano Fagiuoli, Jorg Petersen and Jagpreet Chhatwal, 2019, "Changes in hepatitis C burden and treatment trends in Europe during the era of direct-acting antivirals: A modelling study", BMJ Open, 9, (6)
  • Qiushi Chen, Lei Zhao, Jan C. Fransoo and Zhe Li, 2019, "Dual-mode inventory management under a chance credit constraint", OR Spectrum, 41, (1), pp. 147-178
  • Qiushi Chen, Marc R. Larochelle, Davis T. Weaver, Anna P. Lietz, Peter P. Mueller, Sarah Mercaldo, Sarah E. Wakeman, Kenneth A. Freedberg, Tiana J. Raphel, Amy B. Knudsen, Pari V. Pandharipande and Jagpreet Chhatwal, 2019, "Prevention of prescription opioid misuse and projected overdose deaths in the United States", JAMA Network Open, 2, (2)
  • Jagpreet Chhatwal, Qiushi Chen, Emily D. Bethea, Chin Hur, Anne C. Spaulding and Fasiha Kanwal, 2019, "The impact of direct-acting anti-virals on the hepatitis C care cascade: Identifying progress and gaps towards hepatitis C elimination in the United States", Alimentary Pharmacology & Therapeutics, 50, (1), pp. 66-74
  • Ç Çaglayan, H Terawaki, Qiushi Chen, A Rai, T Ayer and C R Flowers, 2018, "Microsimulation modeling in oncology.", JCO clinical cancer informatics, 2, pp. 1-11
  • J Chhatwal, Qiushi Chen, T Ayer, E D Bethea, F Kanwal, K V Kowdley, X Wang, M S Roberts and S C Gordon, 2018, "Hepatitis C virus re-treatment in the era of direct-acting antivirals: Projections in the USA.", Alimentary pharmacology & therapeutics, 47, (7), pp. 1023-1031
  • E D Bethea, Qiushi Chen, C Hur, R T Chung and J Chhatwal, 2018, "Should we treat acute hepatitis C? A decision and cost-effectiveness analysis.", Hepatology, 67, (3), pp. 837-846
  • Qiushi Chen, Turgay Ayer and Jagpreet Chhatwal, 2018, "Optimal M-switch surveillance policies for liver cancer in a hepatitis C-infected population", Operations Research, 66, (3), pp. 673-696
  • Qiushi Chen, A D Staton, T Ayer, D A Goldstein, J L Koff and C R Flowers, 2017, "Exploring the potential cost-effectiveness of precision medicine treatment strategies for diffuse large B-cell lymphoma.", Leukemia & lymphoma, pp. 1-10
  • R Aggarwal, Qiushi Chen, A Goel, N Seguy, R Pendse, T Ayer and J Chhatwal, 2017, "Cost-effectiveness of hepatitis C treatment using generic direct-acting antivirals available in India.", PloS one, 12, (5), pp. e0176503
  • Qiushi Chen, T Ayer and J Chhatwal, 2017, "Sensitivity analysis in sequential decision models.", Medical decision making, 37, (2), pp. 243-252
  • Qiushi Chen, N Jain, T Ayer, W G Wierda, C R Flowers, S M O'Brien, M J Keating, H M Kantarjian and J Chhatwal, 2017, "Economic burden of chronic lymphocytic leukemia in the era of oral targeted therapies in the United States.", Journal of clinical oncology, 35, (2), pp. 166-174
  • Qiushi Chen, T Ayer, L J Nastoupil, J L Koff, A D Staton, J Chhatwal and C R Flowers, 2016, "Population-specific prognostic models are needed to stratify outcomes for African-Americans with diffuse large B-cell lymphoma.", Leukemia & lymphoma, 57, (4), pp. 842-51
  • D A Goldstein, Qiushi Chen, T Ayer, D H Howard, J Lipscomb, S S Ramalingam, F R Khuri and C R Flowers, 2015, "Necitumumab in metastatic squamous cell lung cancer: Establishing a value-based cost.", JAMA oncology, 1, (9), pp. 1293-300


  • E D Bethea, Qiushi Chen, C Hur, R T Chung and J Chhatwal, 2018, "Reply.", Hepatology, 67, (4), pp. 1641-1642

Research Projects

Honors and Awards

  • First Prize, 2016 INFORMS Decision Analysis Society Student Paper Competition, 2016 - 2016
  • Honorable Mention, 2016 Public Sector Operations Research Best Paper Competition, 2016 - 2016
  • George Fellowship, Georgia Institute of Technology, 2012 - 2013


Service to Penn State:

Service to External Organizations:




Home of the first established industrial engineering program in the world, the Harold and Inge Marcus Department of Industrial and Manufacturing Engineering (IME) at Penn State has made a name for itself in the engineering industry through its storied tradition of unparalleled excellence and innovation in research, education, and outreach.

We are Innovators. We are Makers. We are Excellence in Engineering. We are Penn State IME.

The Harold and Inge Marcus Department of
Industrial and Manufacturing Engineering

310 Leonhard Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-865-7601

FAX: 814-863-4745